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7.1.U1 Nucleosomes help to supercoil the DNA.
7.1.U2 DNA structure suggested a mechanism for DNA replication.
7.1.U3 DNA polymerases can only add nucleotides to the 3’ end of a primer.
7.1.U4 DNA replication is continuous on the leading strand and discontinuous on the lagging strand. [Details of DNA replication differ between prokaryotes and eukaryotes. Only the prokaryotic system is expected.]
7.1.U5 DNA replication is carried out by a complex system of enzymes. [The proteins and enzymes involved in DNA replication should include helicase, DNA gyrase, single strand binding proteins, DNA primase and DNA polymerases I and III.]
7.1.U6 Some regions of DNA do not code for proteins but have other important functions. [The regions of DNA that do not code for proteins should be limited to regulators of gene expression, introns, telomeres and genes for tRNAs.]
7.1.A1 Rosalind Franklin’s and Maurice Wilkins’ investigation of DNA structure by X-ray diffraction.
7.1.A2 Use of nucleotides containing dideoxyribonucleic acid to stop DNA replication in preparation of samples for base sequencing.
7.1.A3 Tandem repeats are used in DNA profiling.
7.1.S1 Analysis of results of the Hershey and Chase experiment providing evidence that DNA is the genetic material.
7.1.S2 Utilization of molecular visualization software to analyse the association between protein and DNA within a nucleosome.
7.1.U2 DNA structure suggested a mechanism for DNA replication.
7.1.U3 DNA polymerases can only add nucleotides to the 3’ end of a primer.
7.1.U4 DNA replication is continuous on the leading strand and discontinuous on the lagging strand. [Details of DNA replication differ between prokaryotes and eukaryotes. Only the prokaryotic system is expected.]
7.1.U5 DNA replication is carried out by a complex system of enzymes. [The proteins and enzymes involved in DNA replication should include helicase, DNA gyrase, single strand binding proteins, DNA primase and DNA polymerases I and III.]
7.1.U6 Some regions of DNA do not code for proteins but have other important functions. [The regions of DNA that do not code for proteins should be limited to regulators of gene expression, introns, telomeres and genes for tRNAs.]
7.1.A1 Rosalind Franklin’s and Maurice Wilkins’ investigation of DNA structure by X-ray diffraction.
7.1.A2 Use of nucleotides containing dideoxyribonucleic acid to stop DNA replication in preparation of samples for base sequencing.
7.1.A3 Tandem repeats are used in DNA profiling.
7.1.S1 Analysis of results of the Hershey and Chase experiment providing evidence that DNA is the genetic material.
7.1.S2 Utilization of molecular visualization software to analyse the association between protein and DNA within a nucleosome.
Bioknowledgy
Alex Lee
Guided Notes
Resources
DNA Structure
DNA by Khan Academy
DNA Anatomy by John Kyrk
Build a DNA Molecule by learn.genetics
DNA Replication
DNA Replication by St Olaf College
DNA Replication by Wiley
DNA Replication visualisation style animation by HHMI
DNA Double Helix Game by Nobelprize.org
DNA Replication (a detailed animation) by John Kyrk
DNA Packaging
DNA Molecule: how DNA is packaged by the DNA Learning Center
Nucleosomes
The 3D packaging of nuclear chromosomes by W H Freeman
Chromatin remodelling by McGraw and Hill
DNA packaging visualisation by HHMIHershey and Chase Experiment
Hershey and Chase Experiment by McGraw and Hill
The Hershey-Chase Experiment by Access Excellence
The Hershey and Chase Experiments by John Kimball
X-Ray diffraction of DNA
Franklin's X-Ray diffraction by the DNA Learning Center
Base sequencing
How to sequence the human genome - Mark J. Kiel
DNA by Khan Academy
DNA Anatomy by John Kyrk
Build a DNA Molecule by learn.genetics
DNA Replication
DNA Replication by St Olaf College
DNA Replication by Wiley
DNA Replication visualisation style animation by HHMI
DNA Double Helix Game by Nobelprize.org
DNA Replication (a detailed animation) by John Kyrk
DNA Packaging
DNA Molecule: how DNA is packaged by the DNA Learning Center
Nucleosomes
The 3D packaging of nuclear chromosomes by W H Freeman
Chromatin remodelling by McGraw and Hill
DNA packaging visualisation by HHMIHershey and Chase Experiment
Hershey and Chase Experiment by McGraw and Hill
The Hershey-Chase Experiment by Access Excellence
The Hershey and Chase Experiments by John Kimball
X-Ray diffraction of DNA
Franklin's X-Ray diffraction by the DNA Learning Center
Base sequencing
How to sequence the human genome - Mark J. Kiel
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